SAP18 and RBM39

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SAP18	RBM39
Gene Name		Sin3A-associated protein, 18kDa	RNA binding motif protein 39
Image
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex ASAP Complex	Nucleoplasm Microtubule Organizing Center Microtubule Cytoskeleton Nuclear Speck
	Molecular Function	Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Chromatin Organization Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter MRNA Processing RNA Splicing Gene Expression Regulation Of Gene Expression, Epigenetic Positive Regulation Of Apoptotic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Splicing
Pathways		NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: HDAC1 IKZF1 INCA1 NOL12 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3	47 interactors: AK8 APP ARL6IP4 BANP C11orf57 CHERP CLK2 DDX39B ESR1 ESR2 FAM200A GOLGA2 HIST1H1C HNRNPH2 HOMEZ JUN KIAA0907 KRTAP12-2 MLX NCOA6 NKAP PGR PHC2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1IP1 SRPK1 SRPK2 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10
Entrez ID		10284	9584
HPRD ID		04256	09201
Ensembl ID		ENSG00000150459	ENSG00000131051
Uniprot IDs		O00422	B4DRA0 Q14498
PDB IDs		2HDE	2JRS
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Chromatin Organization Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Nitrogen Compound Metabolic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Neutrophil Differentiation Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Negative Regulation Of Protein Localization To Nucleus Regulation Of RNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of Histone Modification Positive Regulation Of Chromatin Silencing Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Tubulin Deacetylation Error-prone Translesion Synthesis Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Regulation Of Metabolic Process Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning	RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Metabolic Process Regulation Of Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Mammary Gland Branching Involved In Pregnancy Regulation Of Transcription, DNA-templated Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Process MRNA Export From Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Positive Regulation Of Viral Process Vagina Development RNA Export From Nucleus
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?