HNRNPR and RPL26

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNRNPR	RPL26
Description		heterogeneous nuclear ribonucleoprotein R	ribosomal protein L26
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Endoplasmic Reticulum Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Cytoplasmic Translation RRNA Processing Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To UV Ribosomal Large Subunit Biogenesis Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Translation Cellular Response To Gamma Radiation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Translation Involved In Cellular Response To UV
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Monocyte percentage of white cells ( 32888494)
Interacting Genes		96 interacting genes: ANKRD28 BMPR2 CEBPA CLK3 FARSA FXR2 H3-4 IL7R KHDRBS2 KHDRBS3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEIL3 NFE2L2 OGT PCBP2 PCDHB14 PRMT1 RASD1 RBM3 RPL26 SMN1 SNRPA SUMO2 TAB1 USP7	9 interacting genes: APLP2 EIF4ENIF1 FBXO7 HNRNPR MDM2 NAA10 NAA15 NAA16 SAYSD1
Entrez ID		10236	6154
HPRD ID		06228	04746
Ensembl ID		ENSG00000125944	ENSG00000161970
Uniprot IDs		A0A6Q8PEX7 A0A6Q8PHG0 B4DMB1 B4DMD1 B4DT28 O43390 Q0VGD6	P61254
PDB IDs		2DK2	4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8ONY 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9FPZ 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation MRNA Destabilization Regulation Of Macromolecule Metabolic Process RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Regulation Of Translation Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Migration Negative Regulation Of Signaling Negative Regulation Of Cell Communication	NatA Complex N-terminal Protein Amino Acid Acetylation Acetyltransferase Activity Protein Acetylation Ribosome Binding Acetyltransferase Activator Activity Regulation Of Protein Stability Protein Metabolic Process Macromolecule Metabolic Process Response To Formaldehyde Cellular Response To Vitamin B1 Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Protein Maturation Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Apoptotic Process Protein Modification Process Negative Regulation Of Programmed Cell Death Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Response To Vitamin B1 Response To Water-immersion Restraint Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Ubiquitin Binding Cellular Response To Actinomycin D Protein N-terminal-serine Acetyltransferase Activity Lewy Body Core UFM1-modified Protein Reader Activity NEDD8 Ligase Activity Response To Actinomycin D Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Nucleus Positive Regulation Of Catabolic Process Cellular Response To UV-C Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion Regulation Of G1/S Transition Of Mitotic Cell Cycle Receptor Serine/threonine Kinase Binding Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Localization To Nucleus Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Proteolysis Involved In Protein Catabolic Process Atrial Septum Development
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