NUBP2 and NUBPL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUBP2	NUBPL
Description		NUBP iron-sulfur cluster assembly factor 2, cytosolic	NUBP iron-sulfur cluster assembly factor, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Spindle Pole Centrosome Cell Projection	Mitochondrion Mitochondrial Matrix Plasma Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding ATP-dependent FeS Chaperone Activity	Nucleotide Binding Protein Binding ATP Binding Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding ATP-dependent FeS Chaperone Activity
	Biological Process	Iron-sulfur Cluster Assembly Cell Projection Organization	Mitochondrion Organization Iron-sulfur Cluster Assembly Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Cytosolic iron-sulfur cluster assembly	Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Insulin-like growth factors ( 21216879)	Bitter alcoholic beverage consumption ( 31046077) Brain lesion load ( 19010793) Response to iloperidone treatment (QT prolongation) ( 18521091)
Interacting Genes		12 interacting genes: CYSRT1 INCA1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP9-8 MDFI NOTCH2NLA NUBPL PTGER4 TGM1 TNS2	3 interacting genes: KDM8 MTUS2 NUBP2
Entrez ID		10101	80224
HPRD ID		14846	16600
Ensembl ID		ENSG00000095906	ENSG00000151413
Uniprot IDs		B7Z6P0 H3BQR2 Q9Y5Y2	B3KSK2 B4DWB0 Q8TB37 X5D2R5
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding Negative Regulation Of Eosinophil Extravasation Cornified Envelope	Peptidyl-arginine 3-dioxygenase Activity ATP-dependent FeS Chaperone Activity
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