CCDC179 and SAMD4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC179	SAMD4B
Description		coiled-coil domain containing 179	sterile alpha motif domain containing 4B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		P-body Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process		Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Translation Regulation Of MRNA Stability
Pathways
Drugs
Diseases
GWAS		Thyroid volume in Hashimoto’s thyroiditis ( 32019955)	Alanine aminotransferase levels ( 33339817) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: PPARA SAMD4B ZNF655	8 interacting genes: BCL2L10 CCDC179 CFTR LRRC8E NUTM1 RSRC2 USP53 YWHAG
Entrez ID		100500938	55095
HPRD ID			10960
Ensembl ID		ENSG00000255359	ENSG00000179134
Uniprot IDs		H3BU77	M0QZ22 Q5PRF9 Q66K25 Q8IXP7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Appetite Negative Regulation Of Glycolytic Process Cellular Response To Fructose Stimulus Negative Regulation Of Cholesterol Storage Regulation Of Response To Food MDM2/MDM4 Family Protein Binding Enamel Mineralization Response To Fructose DNA-binding Transcription Activator Activity Negative Regulation Of ATP Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Gluconeogenesis Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Tissue Growth Regulation Of Appetite Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of ATP Biosynthetic Process Tooth Mineralization Negative Regulation Of Lipid Storage NFAT Protein Binding Positive Regulation Of Transformation Of Host Cell By Virus Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of ATP Biosynthetic Process Behavioral Response To Nicotine Positive Regulation Of Fatty Acid Beta-oxidation Mitogen-activated Protein Kinase Kinase Kinase Binding Positive Regulation Of Fatty Acid Oxidation Nuclear Steroid Receptor Activity Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear-transcribed MRNA Poly(A) Tail Shortening Translation Repressor Activity Negative Regulation Of MiRNA Transcription Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Lipid Catabolic Process Lipoprotein Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Fatty Acid Oxidation Reactive Nitrogen Species Metabolic Process Ubiquitin Conjugating Enzyme Binding Regulation Of Response To Nutrient Levels Nitric Oxide Metabolic Process Negative Regulation Of Organ Growth Regulation Of Fatty Acid Transport Lactation Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of ATP Metabolic Process Positive Regulation Of Fatty Acid Metabolic Process
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