CDH6 and CDH18

Number of citations of the paper that reports this interaction (PubMedID 10861224)
34

Data Source:
HPRD (in vitro, in vivo)

		CDH6	CDH18
Description		cadherin 6	cadherin 18
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Adherens Junction Membrane Catenin Complex Cell Junction Synapse Glutamatergic Synapse	Plasma Membrane Adherens Junction Membrane Catenin Complex
	Molecular Function	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Notch Signaling Pathway Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion Synaptic Membrane Adhesion	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion
Pathways		Adherens junctions interactions	Adherens junctions interactions
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alanine aminotransferase levels ( 34315874 33547301) Aspartate aminotransferase levels ( 34315874 33547301) Cocaine dependence ( 31212010) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Emphysema-related traits ( 20709820) Gamma glutamyl transferase levels ( 33339817 29403010) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549 28869591) Late-onset myasthenia gravis ( 26562150) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 22001757) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Resting heart rate ( 27798624) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Sleep (1/3-day periodicity) ( 33075057) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)	Childhood body mass index ( 33045005) Depression (quantitative trait) ( 20800221) Diabetes (gestational) ( 31269844) Erectile dysfunction ( 30583798) Metabolic coherence (transcriptomic) ( 30852652) Mitochondrial DNA levels ( 25240745) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Obstetric antiphospholipid syndrome ( 28424481) Resistant hypertension ( 31545351) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Serum metabolite concentrations in chronic kidney disease ( 29545352) Type 2 diabetes ( 31049640)
Interacting Genes		5 interacting genes: CDH10 CDH18 CDH19 CDH7 CDH9	4 interacting genes: CDH12 CDH6 CDH9 MYOG
Entrez ID		1004	1016
HPRD ID		04305	04314
Ensembl ID		ENSG00000113361	ENSG00000145526
Uniprot IDs		P55285	D6RER2 Q13634
PDB IDs		5VEB
Enriched GO Terms of Interacting Partners?		Catenin Complex Cell-cell Adhesion Mediated By Cadherin Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Junction Assembly Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Assembly Cadherin Binding Cell Motility Cell Junction Organization Cell-cell Adhesion Calcium Ion Binding Cell Adhesion Cell Migration Cellular Component Assembly Anatomical Structure Morphogenesis Synaptic Membrane Adhesion Developmental Process 9+0 Motile Cilium Metal Ion Binding Outer Dynein Arm Axonemal Dynein Complex Lateral Ventricle Development Minus-end-directed Microtubule Motor Activity Plasma Membrane Outer Dynein Arm Assembly Glial Cell Projection Dynein Light Intermediate Chain Binding Presynaptic Active Zone Membrane Postsynaptic Specialization Membrane 9+2 Motile Cilium Dynein Intermediate Chain Binding Dynein Complex Axonemal Dynein Complex Assembly Epithelial Cilium Movement Involved In Extracellular Fluid Movement Extracellular Transport Microtubule Motor Activity	Catenin Complex Cell-cell Adhesion Mediated By Cadherin Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Junction Assembly Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Synaptic Membrane Adhesion Cell Junction Assembly Cadherin Binding Cell Junction Organization Cell-cell Adhesion Calcium Ion Binding Positive Regulation Of Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Cell Adhesion Cell Migration Cell Motility Response To Denervation Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Muscle Atrophy CAMP Biosynthetic Process Adenylate Cyclase Activity Regulation Of Skeletal Muscle Fiber Development Response To Inactivity Adenylate Cyclase Binding Regulation Of Skeletal Muscle Satellite Cell Proliferation Cellular Response To Forskolin Positive Regulation Of Myotube Differentiation Muscle Cell Fate Commitment Regulation Of Skeletal Muscle Cell Proliferation Cellular Response To Lithium Ion Response To Forskolin Response To Lithium Ion Phosphorus-oxygen Lyase Activity Anatomical Structure Morphogenesis Positive Regulation Of Skeletal Muscle Tissue Development CAMP Metabolic Process Cyclic Nucleotide Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Striated Muscle Tissue Development Regulation Of Myoblast Fusion Myotube Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?