SLC25A21-AS1 and L2HGDH

Number of citations of the paper that reports this interaction (PubMedID 36717926)
49

Data Source:
BioGRID (unspecified method)

		SLC25A21-AS1	L2HGDH
Description		SLC25A21 antisense RNA 1	L-2-hydroxyglutarate dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function		Oxidoreductase Activity Oxidoreductase Activity, Acting On CH-OH Group Of Donors 2-hydroxyglutarate Dehydrogenase Activity
	Biological Process		2-oxoglutarate Metabolic Process Small Molecule Metabolic Process
Pathways			Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462 31152163 31451708) Liver enzyme levels (alanine transaminase) ( 33972514) Periodontal disease-related phenotype (Socransky) ( 24347629) Serum metabolite levels ( 33031748) Systolic blood pressure ( 30224653)
Interacting Genes		20 interacting genes: APEX1 ARFGAP1 ARIH1 BROX DAP3 DYNC1LI1 FAM50A GRSF1 GRWD1 KHSRP KPNA1 L2HGDH PAFAH1B1 PPME1 PPP2R1A PSMD6 PTBP3 SLC1A5 TBL2 TXLNA	1 interacting genes: SLC25A21-AS1
Entrez ID		100129794	79944
HPRD ID			12640
Ensembl ID		ENSG00000258708	ENSG00000087299
Uniprot IDs			Q9H9P8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding	Corticospinal Tract Morphogenesis Ciliary Basal Body Centriolar Subdistal Appendage Ciliary Transition Fiber Microtubule Nucleation By Microtubule Organizing Center Corpus Callosum Morphogenesis Centrosome-templated Microtubule Nucleation Establishment Of Left/right Asymmetry Microtubule Anchoring At Centrosome Centriole-centriole Cohesion Microtubule Minus-end Binding Microtubule Anchoring At Microtubule Organizing Center Collateral Sprouting Dynein Axonemal Particle Outer Dynein Arm Assembly Inner Dynein Arm Assembly Axonal Growth Cone Pericentriolar Material Central Nervous System Projection Neuron Axonogenesis Microtubule Anchoring Microtubule Nucleation Central Nervous System Neuron Axonogenesis Centrosome Localization Protein Folding Chaperone Complex Mitotic Spindle Pole Microtubule-based Process Axonemal Dynein Complex Assembly Epithelial Cilium Movement Involved In Extracellular Fluid Movement Nucleolus Extracellular Transport Cytoplasmic Microtubule
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