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CASP8AP2
Gene Name
caspase 8 associated protein 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
PML Body
Molecular Function
DNA Binding
Transcription Corepressor Activity
Death Receptor Binding
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Peptidase Activator Activity Involved In Apoptotic Process
SUMO Polymer Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Cycle
Signal Transduction
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Fas Signaling Pathway
Cellular Response To Mechanical Stimulus
Apoptotic Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
14 interactors:
CALM1
CASP10
CASP8
CREM
CTBP2
FADD
FAS
GLUL
PML
SP100
SREBF2
TRAF2
TRIM21
UBE2I
Entrez ID
9994
HPRD ID
06048
Ensembl ID
Uniprot IDs
Q9UKL3
PDB IDs
2LR8
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Innate Immune Response
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Immune Response
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of Peptidase Activity
Regulation Of Signaling
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Oligomerization
Regulation Of Cysteine-type Endopeptidase Activity
Response To Organic Substance
Positive Regulation Of Metabolic Process
Positive Regulation Of Signal Transduction
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Protein Processing
Defense Response
Regulation Of Signal Transduction
Motor Neuron Apoptotic Process
Extrinsic Apoptotic Signaling Pathway
Viral Process
Positive Regulation Of Proteolysis
Immune System Process
Protein Complex Assembly
TRAIL-activated Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Negative Regulation Of RNA Biosynthetic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Response To Cytokine
Regulation Of Endopeptidase Activity
Programmed Necrotic Cell Death
Necrotic Cell Death
Regulation Of Peptidase Activity
Negative Regulation Of Gene Expression
Necroptotic Signaling Pathway
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
TRIF-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Apoptotic Process
Tagcloud
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arkadia
c5orf25
clustered
custom
dlt
e3s
fitted
flash
idea
jxc1
modifier
pentameric
pias
polysumo
polysumoylation
proteostasis
python
rnf111
rnf4
script
sim
sims
sobp
stresses
string
sumo
sumoylation
transducers
vidlt