USP3

Gene Name		ubiquitin specific peptidase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin
	Molecular Function	Core Promoter Sequence-specific DNA Binding Chromatin Binding Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Zinc Ion Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle DNA Repair Regulation Of Transcription, DNA-templated Histone Deubiquitination Regulation Of Protein Stability Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Heart failure ( 20445134)
Protein-protein Interactions		3 interactors: DDX58 IFIH1 UBC
Entrez ID		9960
HPRD ID		05290
Ensembl ID
Uniprot IDs		Q9Y6I4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type I Interferon Production Regulation Of Type III Interferon Production Detection Of Virus Positive Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Cytoplasmic Pattern Recognition Receptor Signaling Pathway In Response To Virus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway Negative Regulation Of Cytokine Production Regulation Of Innate Immune Response Cellular Response To Virus Positive Regulation Of Interferon-alpha Production Positive Regulation Of Interferon-beta Production Positive Regulation Of Cytokine Production Immune Response-regulating Signaling Pathway Regulation Of Interferon-beta Production Regulation Of Cytokine Production Viral Process Positive Regulation Of Immune Response Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Defense Response To Virus Immune Response Regulation Of Immune System Process Defense Response Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity RIG-I Signaling Pathway Response To Virus Intracellular Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune System Process Viral Protein Processing Protein Modification By Small Protein Conjugation Positive Regulation Of Defense Response To Virus By Host Response To Other Organism Notch Receptor Processing Virion Assembly Response To Biotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Stress Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein Sumoylation Glycogen Biosynthetic Process Intracellular Transport Of Virus Regulation Of Defense Response To Virus By Host Positive Regulation Of Transcription Factor Import Into Nucleus
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