MFN2

Gene Name		mitofusin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Microtubule Cytoskeleton Integral Component Of Membrane Intrinsic Component Of Mitochondrial Outer Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Ubiquitin Protein Ligase Binding
	Biological Process	Blastocyst Formation Protein Targeting To Mitochondrion Autophagy Apoptotic Process Response To Unfolded Protein Mitochondrial Membrane Organization Cell Cycle Arrest Blood Coagulation Mitochondrial Fusion Protein Localization To Pre-autophagosomal Structure Negative Regulation Of Ras Protein Signal Transduction Camera-type Eye Morphogenesis Negative Regulation Of Smooth Muscle Cell Proliferation Mitochondrion Localization
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Platelet counts ( 22139419)
Protein-protein Interactions		1 interactors: MARCH5
Entrez ID		9927
HPRD ID		08495
Ensembl ID		ENSG00000116688
Uniprot IDs		O95140
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging Protein Autoubiquitination Positive Regulation Of Mitochondrion Organization Protein Localization To Mitochondrion Regulation Of Mitochondrion Organization Protein Polyubiquitination
Tagcloud ?		app atrophy biogenesis cognitive compensate defect deficits drp1 dynamin feature fis1 fission injected mfn1 mitochondria mitochondrial mitofusion nsc nscs opa1 optic prominent ps1 rescue susceptible tg transplantation veh vehicle