KLHL21

Description		kelch like family member 21
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Spindle Polar Microtubule Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Cullin Family Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Protein Ubiquitination Regulation Of Cytokinesis Chromosome Passenger Complex Localization To Spindle Midzone Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cell Division
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		5 interacting genes: AURKB CYLD IKBKB KLC3 MAPRE1
Entrez ID		9903
HPRD ID		17239
Ensembl ID		ENSG00000162413
Uniprot IDs		Q9UJP4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Pattern Recognition Receptor Signaling Pathway Attachment Of Mitotic Spindle Microtubules To Kinetochore Spindle Intracellular Receptor Signaling Pathway Activation Of Innate Immune Response Spindle Midzone Regulation Of Microtubule-based Process Mitotic Spindle Pole Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Innate Immune Response Microtubule Immune Response-activating Signaling Pathway Cytoplasmic Microtubule Canonical NF-kappaB Signal Transduction Immune Response-regulating Signaling Pathway Activation Of Immune Response Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Innate Immune Response Positive Regulation Of Defense Response Negative Regulation Of Interleukin-18-mediated Signaling Pathway Regulation Of Cytoskeleton Organization Met1-linked Polyubiquitin Deubiquitinase Activity Cytoskeleton Spindle Assembly Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Localization To Astral Microtubule Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Microtubule Polymerization Or Depolymerization Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Immune Response Centrosome Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Microtubule Cytoskeleton Organization Involved In Mitosis Protein Localization To Mitotic Spindle Protein Localization To Spindle Microtubule Protein Linear Deubiquitination Negative Regulation Of Intracellular Signal Transduction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent IkappaB Kinase Activity Spindle Pole Mitotic Spindle Astral Microtubule End Cortical Microtubule Cytoskeleton Spindle Organization Microtubule-based Process
Tagcloud ?