KLHL21

Gene Name		kelch-like family member 21
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Polar Microtubule Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity
	Biological Process	Mitotic Nuclear Division Protein Ubiquitination Regulation Of Cytokinesis Chromosome Passenger Complex Localization To Spindle Midzone Cell Division
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: AURKB
Entrez ID		9903
HPRD ID		17239
Ensembl ID		ENSG00000162413
Uniprot IDs		Q9UJP4
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-S28 Phosphorylation Spindle Stabilization Abscission Mitotic Spindle Midzone Assembly Cleavage Furrow Formation Mitotic Spindle Elongation Protein Localization To Kinetochore Negative Regulation Of Cytokinesis Spindle Midzone Assembly Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Attachment Of Spindle Microtubules To Kinetochore Histone-serine Phosphorylation Regulation Of B Cell Apoptotic Process Mitotic Spindle Assembly Protein Localization To Chromosome Positive Regulation Of Cytokinesis Negative Regulation Of Microtubule Depolymerization Histone Phosphorylation Mitotic Spindle Organization Spindle Checkpoint Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Cytokinesis Negative Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Protein Binding Microtubule Anchoring Cellular Response To UV Regulation Of Lymphocyte Apoptotic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Spindle Assembly Cellular Response To Light Stimulus Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Binding Cytokinesis Regulation Of Protein Depolymerization Peptidyl-serine Phosphorylation Positive Regulation Of Cell Division Regulation Of Protein Complex Disassembly Spindle Organization Response To UV Cellular Response To Radiation Maintenance Of Protein Location In Cell Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Maintenance Of Protein Location Maintenance Of Location In Cell Negative Regulation Of Cytoskeleton Organization
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