RHOBTB1

Description		Rho related BTB domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Endosome Membrane Cytoplasmic Vesicle Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cell Shape Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways		RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Diastolic blood pressure ( 19430483) Femur bone mineral density x serum urate levels interaction ( 34046847) Food allergy ( 25710614) Lean body mass ( 28552196) Metabolite levels ( 23823483) Milk allergy ( 25710614) Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Novel Interacting Genes		1 novel interacting genes: ARID5B
Interacting Genes		1 interacting genes: CUL5
Entrez ID		9886
HPRD ID		06299
Ensembl ID		ENSG00000072422
Uniprot IDs		O94844
PDB IDs
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Suppression Of Host Innate Immune Response Negative Regulation Of Focal Adhesion Disassembly Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Growth Hormone Receptor Signaling Pathway Ubiquitin Ligase Complex Scaffold Activity Erythropoietin-mediated Signaling Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway Reelin-mediated Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Muscle Organ Morphogenesis Fat Pad Development Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cul5-RING Ubiquitin Ligase Complex Cullin-RING Ubiquitin Ligase Complex Negative Regulation Of CGAS/STING Signaling Pathway Layer Formation In Cerebral Cortex Negative Regulation Of Focal Adhesion Assembly Fibroblast Migration Cell Migration ERBB2 Signaling Pathway Growth Hormone Receptor Signaling Pathway Adrenal Gland Development Female Gonad Development CGAS/STING Signaling Pathway Positive Regulation Of Focal Adhesion Assembly Cell Motility Face Morphogenesis Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Protein K11-linked Ubiquitination Site Of DNA Damage Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Neuron Migration Adipose Tissue Development SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell-matrix Adhesion SCF Ubiquitin Ligase Complex Negative Regulation Of Cell-substrate Adhesion Endoplasmic Reticulum Unfolded Protein Response Regulation Of Focal Adhesion Assembly Connective Tissue Development Regulation Of Cell-substrate Junction Organization ERBB Signaling Pathway Post-embryonic Development Roof Of Mouth Development Calcium Channel Activity Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway
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