CUL7

Gene Name		cullin 7
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Anaphase-promoting Complex Cytoplasm Golgi Apparatus Centrosome Cytosol Cul7-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm 3M Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cytokinesis Vasculogenesis Epithelial To Mesenchymal Transition Placenta Development Proteolysis Ubiquitin-dependent Protein Catabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Golgi Organization Regulation Of Mitotic Nuclear Division Viral Process Protein Ubiquitination Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Positive Regulation Of Dendrite Morphogenesis
Pathways		IRE1alpha activates chaperones Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation XBP1(S) activates chaperone genes Unfolded Protein Response (UPR) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: COMMD1 FBXW8 MEGF10 PLXNB3 RBX1 SKP1 UBE2M
Entrez ID		9820
HPRD ID		09901
Ensembl ID		ENSG00000044090
Uniprot IDs		Q14999
PDB IDs		2JNG
Enriched GO Terms of Interacting Partners?		Protein Neddylation Protein Ubiquitination Protein Modification By Small Protein Conjugation SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Activation Positive Regulation Of Protein Ubiquitination Notch Signaling Pathway Negative Regulation Of Lamellipodium Assembly Regulation Of Protein Ubiquitination Negative Regulation Of Sodium Ion Transmembrane Transport Skeletal Muscle Satellite Cell Differentiation Recognition Of Apoptotic Cell Plasma Membrane To Endosome Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Protein Localization To Cell Surface Histone H2A Monoubiquitination Negative Regulation Of Sodium Ion Transport Histone H2A Ubiquitination Phagocytosis, Recognition Regulation Of Protein Catabolic Process Spongiotrophoblast Layer Development
Tagcloud ?		112g 11p15 1291delt 45m 6psi ccdc8 encompasses genetics ghi ghr height homozygous hypomethylation igf1 igfals imprinting insensitive insensitivity ivs5ds justifying mupd7 obsl1 pseudoexon russell sds srs stat5b stature suspected