DLGAP5

Description		DLG associated protein 5
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GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Cytosol Cytoskeleton Spindle Pole Centrosome Mitotic Spindle
	Molecular Function	Protein Binding Microtubule Binding
	Biological Process	Mitotic Spindle Organization Chromosome Segregation Mitotic Chromosome Movement Towards Spindle Pole Regulation Of Mitotic Cell Cycle Signaling Positive Regulation Of Mitotic Metaphase/anaphase Transition Kinetochore Assembly Centrosome Localization
Pathways		NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS		Protein biomarker ( 23056639) Testicular germ cell tumor ( 28604728)
Interacting Genes		7 interacting genes: APP BTRC EPS15 GOLGA2 MTUS2 TRAF2 TRIM37
Entrez ID		9787
HPRD ID		06490
Ensembl ID		ENSG00000126787
Uniprot IDs		Q15398
PDB IDs		7ZX4 8X9P 9DUQ
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Aggresome Tumor Necrosis Factor Receptor Binding Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Clathrin-coated Pit Negative Regulation Of Catabolic Process Ubiquitin Protein Ligase Activity Protein Autoubiquitination TORC2 Complex Disassembly Protein K63-linked Ubiquitination TORC1 Signaling TOR Signaling Acetylcholine Receptor Activator Activity Intracellular Transport Protein Tetramerization Protein-containing Complex Assembly Lipoprotein Particle Positive Regulation Of Protein Import Negative Regulation Of Autophagy TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Protein Phosphorylated Amino Acid Binding PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Regulation Of Biological Quality Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Regulation Of Protein Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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