PRORP

Name	protein only RNase P catalytic subunit
Structure
Novel Interactors	1 novel interactors: SRP54
Interactors	1 interactors: OGT
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Ribonuclease P Complex Mitochondrial Nucleoid
	Molecular Function	Nuclease Activity Ribonuclease P Activity Hydrolase Activity Metal Ion Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing Mitochondrial TRNA 5'-end Processing
Pathways	tRNA processing in the mitochondrion tRNA modification in the mitochondrion rRNA processing in the mitochondrion
GWAS	No GWAS studies recorded
Entrez ID	9692
HPRD ID	18711
Ensembl ID	ENSG00000100890
Uniprot IDs	O15091
PDB IDs	4ROU 4XGL 4XGM 7ONU 8CBK
GO Terms Enriched among Interactors ?	Signal Recognition Particle Endoplasmic Reticulum Signal Peptide Binding 7S RNA Binding SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Signal Recognition Particle, Endoplasmic Reticulum Targeting SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Exocrine Pancreas Development SRP-dependent Cotranslational Protein Targeting To Membrane Regulation Of Transcription By Glucose NSL Complex Cotranslational Protein Targeting To Membrane Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Acetylglucosaminyltransferase Activity Sin3-type Complex Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Granulocyte Differentiation Protein Targeting To ER Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Intracellular Protein Transmembrane Transport Regulation Of Necroptotic Process Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Rac Protein Signal Transduction Ribonucleoprotein Complex Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Cellular Response To Nutrient Regulation Of Programmed Necrotic Cell Death Protein Transmembrane Transport Protein Targeting To Membrane GDP Binding Neutrophil Chemotaxis Granulocyte Chemotaxis Protein-containing Complex Organization Protein-containing Complex Assembly Neutrophil Migration Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Regulation Of Stem Cell Population Maintenance