LRRC14

Description		leucine rich repeat containing 14
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Kinase Binding
	Biological Process	Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Toll-like Receptor Signaling Pathway
Pathways		Regulation of NF-kappa B signaling
Drugs
Diseases
GWAS		Blood metabolite levels ( 26401656) Cognitive ability (MTAG) ( 29186694) Educational attainment ( 25201988) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Red cell distribution width ( 32888494)
Novel Interacting Genes		2 novel interacting genes: FOXH1 GPAA1
Interacting Genes
Entrez ID		9684
HPRD ID		14312
Ensembl ID		ENSG00000160959
Uniprot IDs		Q15048
PDB IDs
Enriched GO Terms of Interacting Partners?		GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex Maintenance Of Protein Localization In Endoplasmic Reticulum Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI Anchored Protein Biosynthesis Protein Retention In ER Lumen Axial Mesoderm Development Activin Responsive Factor Complex Embryonic Heart Tube Anterior/posterior Pattern Specification Nodal Signaling Pathway Cardiac Right Ventricle Morphogenesis Determination Of Left/right Asymmetry In Lateral Mesoderm Ventricular Trabecula Myocardium Morphogenesis Co-SMAD Binding Hepatocyte Differentiation Heart Field Specification Secondary Heart Field Specification Specification Of Animal Organ Identity Negative Regulation Of Androgen Receptor Signaling Pathway GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Nuclear Androgen Receptor Binding Heart Trabecula Morphogenesis Aorta Morphogenesis Activin Receptor Signaling Pathway BHLH Transcription Factor Binding Cardiac Ventricle Morphogenesis R-SMAD Binding Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Maintenance Of Protein Localization In Organelle Ventricular Cardiac Muscle Tissue Morphogenesis SMAD Binding Maintenance Of Protein Location In Cell Mesoderm Development Cardiac Muscle Tissue Morphogenesis Maintenance Of Protein Location Artery Morphogenesis Outflow Tract Morphogenesis Heart Looping Glycolipid Biosynthetic Process Embryonic Heart Tube Morphogenesis Maintenance Of Location In Cell Muscle Tissue Morphogenesis Maintenance Of Location Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cis-regulatory Region Sequence-specific DNA Binding Glycolipid Metabolic Process Determination Of Bilateral Symmetry
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