GDA

Description		guanine deaminase
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Zinc Ion Binding Guanine Deaminase Activity Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Metal Ion Binding
	Biological Process	Allantoin Metabolic Process Nucleobase-containing Compound Metabolic Process Guanine Catabolic Process Deoxyguanosine Catabolic Process Nervous System Development Amide Catabolic Process GMP Catabolic Process DGMP Catabolic Process Guanine Metabolic Process
Pathways		Purine catabolism
Drugs
Diseases
GWAS		Suicidal ideation ( 20877300)
Interacting Genes		4 interacting genes: DLG1 DLG3 DLG4 SNTA1
Entrez ID		9615
HPRD ID		08849
Ensembl ID		ENSG00000119125
Uniprot IDs		Q9Y2T3
PDB IDs		2UZ9 3E0L 4AQL
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Ionotropic Glutamate Receptor Binding Receptor Localization To Synapse Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Synapse Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Protein Localization To Cell Junction Kinase Binding Postsynaptic Density Membrane Establishment Or Maintenance Of Cell Polarity Adherens Junction Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane AMPA Glutamate Receptor Complex Protein Localization To Postsynaptic Membrane Chemical Synaptic Transmission Protein Localization To Postsynapse Protein Localization To Membrane Neuron Projection Trans-synaptic Signaling Regulation Of Sodium Ion Transmembrane Transport Synaptic Signaling Phosphatase Binding Regulation Of Membrane Potential Protein Kinase Binding Cell-cell Adhesion Synaptic Membrane Lateral Plasma Membrane Regulation Of Sodium Ion Transport Protein-containing Complex Localization Localization Within Membrane Regulation Of System Process Glutamatergic Synapse PDZ Domain Binding Nervous System Development Cell-cell Signaling Signaling Cell Communication P2Y1 Nucleotide Receptor Binding Sarcolemma Bicellular Tight Junction Transmembrane Transporter Binding Cell Adhesion Regulation Of Biological Quality Structural Constituent Of Postsynaptic Density L27 Domain Binding Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior System Development
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