AKAP12

Description		A-kinase anchoring protein 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Membrane Neuronal Cell Body Schaffer Collateral - CA1 Synapse
	Molecular Function	Protein Binding Calmodulin Binding Adenylate Cyclase Binding Protein Kinase A Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Protein Kinase A Signaling Positive Regulation Of Protein Kinase A Signaling Response To Lipopolysaccharide Positive Regulation Of Tumor Necrosis Factor Production Hepatic Stellate Cell Activation Negative Regulation Of Vascular Permeability Modulation Of Chemical Synaptic Transmission Response To Electrical Stimulus Positive Regulation Of Hepatic Stellate Cell Migration Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Regulation Of Protein Kinase C Signaling Positive Regulation Of Oligodendrocyte Apoptotic Process
Pathways		RHOD GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Chronic myeloid leukemia ( 21540461) Coronary artery disease ( 29212778) Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) Delirium ( 29631748) Femur bone mineral density x serum urate levels interaction ( 34046847) Heel bone mineral density ( 30598549) Nevus count or cutaneous melanoma ( 32341527) Refractive error ( 32231278) Type 2 diabetes ( 25760438) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		1 novel interacting genes: SYNE1
Interacting Genes		9 interacting genes: ADRB2 CDK1 EGFR ERBB2 GRK2 PLK1 PRKAR2A PRKCA PTEN
Entrez ID		9590
HPRD ID		05263
Ensembl ID		ENSG00000131016
Uniprot IDs		Q02952 Q86TJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Membrane Disassembly Membrane Disassembly Nuclear Membrane Disassembly Protein Kinase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Kinase Activity Enzyme Binding Nuclear Membrane Organization Regulation Of Mitotic Cell Cycle Nucleotide Binding ERBB2-EGFR Signaling Pathway Regulation Of Growth Intracellular Signal Transduction Anaphase-promoting Complex Binding Negative Regulation Of Multicellular Organismal Process Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Protein Phosphorylation Symbiont Entry Into Host Cell Golgi Organization ATP Binding Phosphorylation Positive Regulation Of Mitotic Cell Cycle Protein Serine/threonine Kinase Activity Negative Regulation Of Muscle Contraction Negative Regulation Of Apoptotic Process Intracellular Signaling Cassette Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Phase Transition Regulation Of Protein Localization Positive Regulation Of Protein Localization Negative Regulation Of Programmed Cell Death ERBB2 Signaling Pathway Positive Regulation Of MAPK Cascade Biological Process Involved In Interaction With Host Negative Regulation Of Mitotic Cell Cycle Phase Transition Protein Localization To Site Of Double-strand Break Regulation Of Cellular Component Organization Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Excitatory Postsynaptic Potential Receptor Complex Identical Protein Binding Transferase Activity Regulation Of Cell Cycle Positive Regulation Of Epithelial Cell Proliferation Central Nervous System Neuron Axonogenesis Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of System Process Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?