ENTPD4

Description		ectonucleoside triphosphate diphosphohydrolase 4
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Lysosome Lysosomal Membrane Golgi Apparatus Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity GDP Phosphatase Activity Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Ribonucleoside Triphosphate Phosphatase Activity CDP Phosphatase Activity CTPase Activity UDP Phosphatase Activity
	Biological Process	UDP Catabolic Process Purine Ribonucleotide Metabolic Process Pyrimidine Ribonucleotide Catabolic Process Nucleobase-containing Small Molecule Catabolic Process CTP Metabolic Process GDP Catabolic Process
Pathways		Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Birth weight ( 31043758) Height ( 31562340) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Thyroid stimulating hormone levels ( 32769997)
Novel Interacting Genes		1 novel interacting genes: PPP3CC
Interacting Genes		1 interacting genes: RPS27
Entrez ID		9583
HPRD ID		09618
Ensembl ID		ENSG00000197217
Uniprot IDs		Q9Y227
PDB IDs		6WG5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Synaptic Vesicle Endocytosis Negative Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Synaptic Vesicle Recycling Calcium-dependent Protein Serine/threonine Phosphatase Activity Protein Serine/threonine Phosphatase Complex Presynapse Positive Regulation Of Calcium Ion Import Across Plasma Membrane Calmodulin-dependent Protein Phosphatase Activity Glutamatergic Synapse Calcineurin Complex Negative Regulation Of Calcium Ion Import Regulation Of Calcium Ion Import Across Plasma Membrane Ribosomal Small Subunit Assembly Positive Regulation Of Calcineurin-NFAT Signaling Cascade Calcineurin-NFAT Signaling Cascade Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Calcium Ion Import Calcineurin-mediated Signaling Regulation Of Synaptic Vesicle Recycling Regulation Of Calcineurin-mediated Signaling Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcineurin-NFAT Signaling Cascade Cytosolic Small Ribosomal Subunit Regulation Of Calcium Ion Import Negative Regulation Of Calcium Ion Transport Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Small-subunit Processome Ribosomal Small Subunit Biogenesis Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Regulation Of Calcium-mediated Signaling Negative Regulation Of Monoatomic Ion Transport Positive Regulation Of Calcium Ion Transport Cytosolic Ribosome GABA-ergic Synapse Negative Regulation Of Transmembrane Transport Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Cytoplasmic Translation Dephosphorylation Phosphoprotein Phosphatase Activity Regulation Of Calcium Ion Transmembrane Transport Structural Constituent Of Ribosome
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