CD38

Description		CD38 molecule
Image
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Nuclear Membrane Extracellular Exosome
	Molecular Function	Transferase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Phosphorus-oxygen Lyase Activity Identical Protein Binding NAD+ Nucleosidase Activity, Cyclic ADP-ribose Generating
	Biological Process	Response To Hypoxia Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Female Pregnancy Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Response To Hormone Negative Regulation Of Neuron Projection Development Artery Smooth Muscle Contraction NAD+ Metabolic Process Positive Regulation Of Cell Growth Positive Regulation Of B Cell Proliferation Positive Regulation Of Insulin Secretion Response To Estradiol Response To Retinoic Acid Response To Progesterone Response To Hydroperoxide Response To Cytokine B Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Bone Resorption Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Vasoconstriction B Cell Receptor Signaling Pathway Long-term Synaptic Depression Response To Interleukin-1 Apoptotic Signaling Pathway
Pathways		Nicotinate metabolism
Drugs		Daratumumab Isatuximab Mezagitamab
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639) Parkinson's disease ( 27182965 28892059)
Novel Interacting Genes		1 novel interacting genes: PCDH7
Interacting Genes		6 interacting genes: CBL CD4 CD9 FCGR3A LCK PECAM1
Entrez ID		952
HPRD ID		00116
Ensembl ID		ENSG00000004468
Uniprot IDs		B4E006 P28907
PDB IDs		1YH3 1ZVM 2EF1 2HCT 2I65 2I66 2I67 2O3Q 2O3R 2O3S 2O3T 2O3U 2PGJ 2PGL 3DZF 3DZG 3DZH 3DZI 3DZJ 3DZK 3F6Y 3I9M 3I9N 3OFS 3RAJ 3ROK 3ROM 3ROP 3ROQ 3U4H 3U4I 4CMH 4F45 4F46 4OGW 4TMF 4XJS 4XJT 5F1K 5F1O 5F21 6EDR 6VUA 7DHA 7DUO 7VKE 8BYU 8D0M 8IL3 8P8C 8VAU 9GOX 9GOY
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Membrane Membrane Raft External Side Of Plasma Membrane Plasma Membrane Cell Activation Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Leukocyte Degranulation Protein Tyrosine Kinase Binding Phosphotyrosine Residue Binding Cell Adhesion Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Immune System Process Positive Regulation Of Lymphocyte Activation Clathrin-coated Endocytic Vesicle Membrane Interleukin-16 Binding Interleukin-16 Receptor Activity Positive Regulation Of Cell Activation Helper T Cell Enhancement Of Adaptive Immune Response Platelet Activation Protein Kinase Binding Positive Regulation Of Intracellular Signal Transduction Vesicle-mediated Transport Endocytosis Positive Regulation Of MAPK Cascade Lymphocyte Activation Regulated Exocytosis Response To Methamphetamine Hydrochloride Regulation Of Cell-cell Adhesion Low-affinity IgG Receptor Activity Immune Receptor Activity Endothelial Cell-matrix Adhesion Regulation Of Lymphocyte Activation Response To Ethanol Symbiont Entry Into Host Cell Cell Recognition Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Leukocyte Activation Myoblast Fusion Involved In Skeletal Muscle Regeneration Fc-gamma Receptor III Complex Import Into Cell Regulation Of Rap Protein Signal Transduction Membrane Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation T Cell Differentiation CD8 Receptor Binding Positive Regulation Of Protein Localization To Cell-cell Junction
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