SPTLC2

Gene Name		serine palmitoyltransferase, long chain base subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Serine C-palmitoyltransferase Complex
	Molecular Function	Serine C-palmitoyltransferase Activity Pyridoxal Phosphate Binding
	Biological Process	Sphingolipid Metabolic Process Sphingomyelin Biosynthetic Process Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Sphinganine Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs		Pyridoxal Phosphate L-Serine
Diseases
GWAS
Protein-protein Interactions		2 interactors: NOTCH3 SPTLC1
Entrez ID		9517
HPRD ID		05755
Ensembl ID		ENSG00000100596
Uniprot IDs		O15270
PDB IDs
Enriched GO Terms of Interacting Partners?		Sphinganine Biosynthetic Process Sphinganine Metabolic Process Sphingomyelin Biosynthetic Process Sphingosine Biosynthetic Process Sphingoid Biosynthetic Process Glomerular Capillary Formation Sphingosine Metabolic Process Sphingomyelin Metabolic Process Glomerulus Morphogenesis Notch Receptor Processing Glomerulus Vasculature Development Ceramide Biosynthetic Process Positive Regulation Of Smooth Muscle Cell Proliferation Glomerulus Development Sphingolipid Biosynthetic Process Neuron Fate Commitment Ceramide Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Cellular Biogenic Amine Metabolic Process Notch Signaling Pathway Amine Metabolic Process Nephron Development Sphingolipid Metabolic Process Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		a2 annexin attracted boyden cd74 cdk5 chamber chemotactic clues col11a1 f3 glioblastoma glioma gliomas gliotropism harbor histologically migrate mobile pd98057 proteomics prove reach rescovitine throughput timp tnfsf8 tropism u87