SLC4A8

Gene Name		solute carrier family 4, sodium bicarbonate cotransporter, member 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Neuronal Cell Body Membrane Neuron Projection
	Molecular Function	Inorganic Anion Exchanger Activity Sodium:bicarbonate Symporter Activity
	Biological Process	Ion Transport Bicarbonate Transport Sodium Ion Transmembrane Transport Regulation Of Intracellular PH Transmembrane Transport Anion Transmembrane Transport
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport Bicarbonate transporters
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-protein Interactions		3 interactors: CA2 CFTR SLC9A3R1
Entrez ID		9498
HPRD ID		05430
Ensembl ID		ENSG00000050438
Uniprot IDs		B4DHY0 E7EML0 F5GZ31 Q2Y0W8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Chloride Transport Bicarbonate Transport Organic Anion Transport Cellular Ion Homeostasis Regulation Of Intracellular PH Regulation Of Cellular PH Cellular Chemical Homeostasis Ion Homeostasis Regulation Of Ion Transport Anion Transport Cellular Homeostasis Regulation Of PH Chemical Homeostasis Regulation Of Anion Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Renal Phosphate Ion Absorption Positive Regulation Of Voltage-gated Chloride Channel Activity Homeostatic Process Response To Estrogen Positive Regulation Of Dipeptide Transmembrane Transport Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Ion Transport Positive Regulation Of Cellular PH Reduction Lipid Transport Lipid Localization Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Iodide Transport Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Angiotensin-activated Signaling Pathway Transepithelial Chloride Transport Regulation Of Ion Transmembrane Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Cation Homeostasis Response To Steroid Hormone Bile Acid Secretion Oligopeptide Transport Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Transepithelial Transport Intracellular PH Elevation Phosphate Ion Homeostasis Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, GABAergic
Tagcloud ?		adaptive beginning cb cch cerebellum cx decreases durations exchanger exhibits hc hco hypothesize nbcn1 nbcn2 ncbt ncbts ndcbe neonates normoxia p2 p90 polyclonal pyramidal rodent scx stabilizes subcortex transporters