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SLC4A8
Gene Name
solute carrier family 4, sodium bicarbonate cotransporter, member 8
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Neuronal Cell Body Membrane
Neuron Projection
Molecular Function
Inorganic Anion Exchanger Activity
Sodium:bicarbonate Symporter Activity
Biological Process
Ion Transport
Bicarbonate Transport
Sodium Ion Transmembrane Transport
Regulation Of Intracellular PH
Transmembrane Transport
Anion Transmembrane Transport
Pathways
Transport of inorganic cations/anions and amino acids/oligopeptides
SLC-mediated transmembrane transport
Bicarbonate transporters
Drugs
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Protein-protein Interactions
3 interactors:
CA2
CFTR
SLC9A3R1
Entrez ID
9498
HPRD ID
05430
Ensembl ID
ENSG00000050438
Uniprot IDs
B4DHY0
E7EML0
F5GZ31
Q2Y0W8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Chloride Transport
Bicarbonate Transport
Organic Anion Transport
Cellular Ion Homeostasis
Regulation Of Intracellular PH
Regulation Of Cellular PH
Cellular Chemical Homeostasis
Ion Homeostasis
Regulation Of Ion Transport
Anion Transport
Cellular Homeostasis
Regulation Of PH
Chemical Homeostasis
Regulation Of Anion Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Renal Phosphate Ion Absorption
Positive Regulation Of Voltage-gated Chloride Channel Activity
Homeostatic Process
Response To Estrogen
Positive Regulation Of Dipeptide Transmembrane Transport
Negative Regulation Of Sodium:proton Antiporter Activity
Glutathione Transport
Ion Transport
Positive Regulation Of Cellular PH Reduction
Lipid Transport
Lipid Localization
Renal Sodium Ion Transport
Cellular Phosphate Ion Homeostasis
Regulation Of Sodium:proton Antiporter Activity
Iodide Transport
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Negative Regulation Of Sodium Ion Transmembrane Transport
Angiotensin-activated Signaling Pathway
Transepithelial Chloride Transport
Regulation Of Ion Transmembrane Transport
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Cellular Cation Homeostasis
Response To Steroid Hormone
Bile Acid Secretion
Oligopeptide Transport
Negative Regulation Of Sodium Ion Transport
Renal Absorption
Regulation Of Proton Transport
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Transepithelial Transport
Intracellular PH Elevation
Phosphate Ion Homeostasis
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Positive Regulation Of Synaptic Transmission, GABAergic
Tagcloud
?
adaptive
beginning
cb
cch
cerebellum
cx
decreases
durations
exchanger
exhibits
hc
hco
hypothesize
nbcn1
nbcn2
ncbt
ncbts
ndcbe
neonates
normoxia
p2
p90
polyclonal
pyramidal
rodent
scx
stabilizes
subcortex
transporters