PIGB

Name	phosphatidylinositol glycan anchor biosynthesis class B
Structure	No pdb structure
Novel Interactors	2 novel interactors: RHEB SMAD6
Interactors	None recorded
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Alpha-1,2-mannosyltransferase Activity GPI Mannosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process
Pathways	Synthesis of glycosylphosphatidylinositol (GPI)
GWAS	No GWAS studies recorded
Entrez ID	9488
HPRD ID	04988
Ensembl ID	ENSG00000069943
Uniprot IDs	Q92521
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Zygotic Specification Of Dorsal/ventral Axis Activin Receptor Binding Dorsal/ventral Axis Specification Aortic Valve Morphogenesis Artery Development Ureteric Bud Development I-SMAD Binding Outflow Tract Septum Morphogenesis Cardiac Septum Development Heart Valve Development Response To Fluid Shear Stress Heteromeric SMAD Protein Complex Transcription Regulator Inhibitor Activity SMAD Protein Signal Transduction Atrioventricular Valve Morphogenesis Intracellular Signaling Cassette Negative Regulation Of Activin Receptor Signaling Pathway Type I Activin Receptor Binding Negative Regulation Of SMAD Protein Signal Transduction Co-SMAD Binding Pulmonary Valve Morphogenesis Mesonephric Epithelium Development Type I Transforming Growth Factor Beta Receptor Binding Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Ossification Aorta Development Mesonephric Tubule Development R-SMAD Binding Embryonic Axis Specification Response To Laminar Fluid Shear Stress Negative Regulation Of Multicellular Organismal Process Ventricular Septum Development Mitral Valve Morphogenesis Coronary Vasculature Development Protein Sequestering Activity Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Translational Initiation Oligodendrocyte Differentiation Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Translational Initiation Protein Kinase Activator Activity Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Oligodendrocyte Differentiation Response To External Biotic Stimulus Golgi Apparatus Positive Regulation Of MiRNA Transcription Heart Valve Morphogenesis Negative Regulation Of Osteoblast Differentiation Regulation Of SMAD Protein Signal Transduction