PIGB

Description		phosphatidylinositol glycan anchor biosynthesis class B
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Alpha-1,2-mannosyltransferase Activity GPI Mannosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: RHEB SMAD6
Interacting Genes
Entrez ID		9488
HPRD ID		04988
Ensembl ID		ENSG00000069943
Uniprot IDs		Q92521
PDB IDs
Enriched GO Terms of Interacting Partners?		Zygotic Specification Of Dorsal/ventral Axis Activin Receptor Binding Dorsal/ventral Axis Specification Aortic Valve Morphogenesis Artery Development Ureteric Bud Development I-SMAD Binding Outflow Tract Septum Morphogenesis Cardiac Septum Development Heart Valve Development Response To Fluid Shear Stress Heteromeric SMAD Protein Complex Transcription Regulator Inhibitor Activity SMAD Protein Signal Transduction Atrioventricular Valve Morphogenesis Intracellular Signaling Cassette Negative Regulation Of Activin Receptor Signaling Pathway Type I Activin Receptor Binding Negative Regulation Of SMAD Protein Signal Transduction Co-SMAD Binding Pulmonary Valve Morphogenesis Mesonephric Epithelium Development Type I Transforming Growth Factor Beta Receptor Binding Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Ossification Aorta Development Mesonephric Tubule Development R-SMAD Binding Embryonic Axis Specification Response To Laminar Fluid Shear Stress Negative Regulation Of Multicellular Organismal Process Ventricular Septum Development Mitral Valve Morphogenesis Coronary Vasculature Development Protein Sequestering Activity Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Translational Initiation Oligodendrocyte Differentiation Positive Regulation Of Glial Cell Differentiation Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Translational Initiation Protein Kinase Activator Activity Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Oligodendrocyte Differentiation Response To External Biotic Stimulus Golgi Apparatus Positive Regulation Of MiRNA Transcription Heart Valve Morphogenesis Negative Regulation Of Osteoblast Differentiation Regulation Of SMAD Protein Signal Transduction
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