TM9SF2

Description		transmembrane 9 superfamily member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Endosome Membrane Membrane Extracellular Exosome
	Molecular Function
	Biological Process	Ceramide Metabolic Process Glycosphingolipid Biosynthetic Process Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Protein Localization To Membrane
Pathways
Drugs
Diseases
GWAS		Asthma ( 30929738 31619474 32296059 34103634) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 26962152)
Interacting Genes		4 interacting genes: AQP2 HTR2C RAB9A SMAD4
Entrez ID		9375
HPRD ID		09198
Ensembl ID		ENSG00000125304
Uniprot IDs		A0A024QYR8 Q99805
PDB IDs
Enriched GO Terms of Interacting Partners?		Lumenal Side Of Membrane Cellular Response To Mercury Ion Cellular Response To Water Deprivation Cytoplasmic Vesicle Membrane Chemical Homeostasis Glycerol Transmembrane Transporter Activity Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Intracellular Signaling Cassette Regulation Of Secretion Regulation Of Secretion By Cell Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Negative Regulation Of Cardiac Myofibril Assembly Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Renal Water Transport Response To Water Deprivation Glycerol Transmembrane Transport Water Transmembrane Transporter Activity Tube Development Homeostatic Process Regulation Of Hormone Secretion Regulation Of ERK1 And ERK2 Cascade G Protein-coupled Serotonin Receptor Complex Phospholipase C-activating Serotonin Receptor Signaling Pathway Regulation Of Corticotropin-releasing Hormone Secretion SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Positive Regulation Of Secretion By Cell Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Polyol Transmembrane Transport Metanephric Collecting Duct Development Response To Mercury Ion Serotonin Binding
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