GLP2R

Description		glucagon like peptide 2 receptor
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Glucagon Receptor Activity Peptide Hormone Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Cellular Response To Glucagon Stimulus
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors
Drugs		Glucagon Teduglutide
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) GIP levels in response to oral glucose tolerance test (fasting) ( 29093273) Iron status biomarkers (ferritin levels) ( 33536631) Type 2 diabetes ( 28566273 30297969)
Interacting Genes		3 interacting genes: CALM1 GCG TRIM54
Entrez ID		9340
HPRD ID		04713
Ensembl ID		ENSG00000065325
Uniprot IDs		A0A384MTS7 B2RAN4 O95838
PDB IDs		7D68
Enriched GO Terms of Interacting Partners?		Mitochondrion-endoplasmic Reticulum Membrane Tethering Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Autophagosome Membrane Docking Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Calcium Ion Transport Regulation Of Metal Ion Transport Glucagon Receptor Binding Gastric Inhibitory Polypeptide Receptor Binding Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Monoatomic Ion Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Glucagon Stimulus Titin Binding Protein Kinase A Signaling Regulation Of Voltage-gated Calcium Channel Activity Detection Of Calcium Ion Calcium Channel Inhibitor Activity Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Response To Glucagon Negative Regulation Of Transporter Activity Cellular Response To Interferon-beta Catalytic Complex Presynaptic Cytosol Calcium Channel Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Cell Action Potential Calcineurin-mediated Signaling Positive Regulation Of Calcium Ion Import Positive Regulation Of Gluconeogenesis Myelin Sheath Negative Regulation Of Microtubule Depolymerization G Protein-coupled Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Response To Interferon-beta Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Microtubule Depolymerization Microtubule Associated Complex Negative Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
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