NEURL3

Description		neuralized E3 ubiquitin protein ligase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome
	Molecular Function	Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Immune System Process Protein Ubiquitination Negative Regulation Of MAPK Cascade Innate Immune Response Ubiquitin-dependent Endocytosis ERK1 And ERK2 Cascade Positive Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Pulse pressure ( 30578418)
Novel Interacting Genes		1 novel interacting genes: LMAN2L
Interacting Genes		3 interacting genes: CCNDBP1 CFLAR UBC
Entrez ID		93082
HPRD ID		14296
Ensembl ID		ENSG00000163121
Uniprot IDs		A0A087WVI2 A0A087WXE0 Q96EH8
PDB IDs
Enriched GO Terms of Interacting Partners?		Ripoptosome Negative Regulation Of Hepatocyte Apoptotic Process Skeletal Myofibril Assembly Negative Regulation Of Myoblast Fusion Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Death-inducing Signaling Complex Skeletal Muscle Atrophy CD95 Death-inducing Signaling Complex Skeletal Muscle Adaptation Striated Muscle Atrophy Positive Regulation Of Glomerular Mesangial Cell Proliferation Muscle Atrophy Positive Regulation Of Cell Proliferation Involved In Kidney Development Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Hepatocyte Proliferation Regulation Of Glomerular Mesangial Cell Proliferation Protein Tag Activity Regulation Of Skeletal Muscle Cell Proliferation Cellular Response To Nitric Oxide Death Receptor Binding Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Hepatocyte Proliferation Regulation Of Skeletal Muscle Satellite Cell Proliferation Cellular Response To Reactive Nitrogen Species Regulation Of Myoblast Fusion Skeletal Muscle Tissue Regeneration Response To Nitric Oxide D-mannose Binding
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