S1PR2

Gene Name		sphingosine-1-phosphate receptor 2
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	G-protein Coupled Receptor Binding G-protein Coupled Receptor Activity Integrin Binding Lipid Binding Sphingosine-1-phosphate Receptor Activity
	Biological Process	Activation Of MAPK Activity Sphingosine-1-phosphate Signaling Pathway G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cell Proliferation Negative Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Establishment Of Endothelial Barrier
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: GNA13 GNAI1 GNAQ
Entrez ID		9294
HPRD ID		05488
Ensembl ID
Uniprot IDs		O95136
PDB IDs		1ZTI
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Wound Healing Cell Activation Response To Wounding Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway Neuron Remodeling Regulation Of Melanocyte Differentiation Activation Of Phospholipase D Activity Maternal Behavior Cell Surface Receptor Signaling Pathway Regulation Of Catenin Import Into Nucleus Regulation Of Developmental Pigmentation Response To Stress Neuron Maturation Cardiovascular System Development Dopamine Receptor Signaling Pathway Forebrain Neuron Development Positive Regulation Of Hydrolase Activity Patterning Of Blood Vessels Activation Of Phospholipase C Activity Vesicle Fusion Embryo Development Positive Regulation Of Phospholipase C Activity Rho Protein Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Forebrain Neuron Differentiation Glutamate Receptor Signaling Pathway Developmental Pigmentation Embryonic Digit Morphogenesis Organelle Fusion Forebrain Generation Of Neurons Action Potential Signal Transduction Protein Stabilization Positive Regulation Of Catalytic Activity Signaling Central Nervous System Neuron Development Cell Communication Pigmentation
Tagcloud ?		altogether bioactive chl contiguous dissemination fty720 functionally gi governs h2 hd1 heterotrimeric hodgkin jte013 km lymphatic lymphoma membranous neoplasm potentiated potently reed s1pr1 sphingolipid sphingosine sternberg sup vpc44116