SLC24A1

Description		solute carrier family 24 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Outer Membrane Neuronal Cell Body
	Molecular Function	Calcium Channel Activity Protein Binding Calcium, Potassium:sodium Antiporter Activity Symporter Activity Antiporter Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Intracellular Calcium Ion Homeostasis Visual Perception Response To Light Intensity Sodium Ion Transmembrane Transport Transmembrane Transport Long-term Synaptic Potentiation Long-term Synaptic Depression Calcium Ion Transmembrane Transport Potassium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways		Activation of the phototransduction cascade Sodium/Calcium exchangers Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D)
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Iron status biomarkers (ferritin levels) ( 33536631) Logical memory (delayed recall) in normal cognition ( 29274321) Mean corpuscular hemoglobin ( 20139978)
Novel Interacting Genes		3 novel interacting genes: PACS1 SLC27A2 TCF12
Interacting Genes		1 interacting genes: CNGA1
Entrez ID		9187
HPRD ID		04685
Ensembl ID		ENSG00000074621
Uniprot IDs		B4DUG1 B4E1W0 F5H127 F5H483 O60721
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Cyclic Nucleotide Activated Cation Channel Complex Intracellularly CAMP-activated Cation Channel Activity CGMP Binding Intracellularly Cyclic Nucleotide-activated Monoatomic Cation Channel Activity Photoreceptor Outer Segment Membrane Intracellularly CGMP-activated Cation Channel Activity Rod Photoreceptor Outer Segment HMG Box Domain Binding Response To Gonadotropin-releasing Hormone CAMP Response Element Binding Pristanate-CoA Ligase Activity Phytanate-CoA Ligase Activity Fatty Acid Transmembrane Transporter Activity Very Long-chain Fatty Acid-CoA Ligase Activity Very Long-chain Fatty Acid Catabolic Process Methyl-branched Fatty Acid Metabolic Process Long-chain Fatty Acid-CoA Ligase Activity Cholate-CoA Ligase Activity Arachidonate-CoA Ligase Activity Fatty Acid Alpha-oxidation Lipid Import Into Cell Long-chain Fatty Acid Import Into Cell Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase COPI-coated Vesicle Long-chain Fatty Acid Transmembrane Transporter Activity CAMP Binding Bile Acid Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Protein Localization To Golgi Apparatus BHLH Transcription Factor Binding
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