LIN52

Description		lin-52 DREAM MuvB core complex component
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GO Annotations	Cellular Component	Nucleoplasm DRM Complex
	Molecular Function	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Chronotype ( 30696823) Macular thickness ( 30535121) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Novel Interacting Genes		3 novel interacting genes: DNAL1 NEK9 RPS6KL1
Interacting Genes		4 interacting genes: DYRK1A EPM2AIP1 MAGEA6 RBL2
Entrez ID		91750
HPRD ID		18708
Ensembl ID		ENSG00000205659
Uniprot IDs		B3KN83 Q52LA3
PDB IDs		4YOO 6C48
Enriched GO Terms of Interacting Partners?		Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Histone H3T45 Kinase Activity
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