MAP3K13

Gene Name		mitogen-activated protein kinase kinase kinase 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	IkappaB Kinase Complex Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Activation Of MAPKK Activity Protein Phosphorylation JNK Cascade Protein Autophosphorylation Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)
Protein-protein Interactions		7 interactors: GLO1 HLA-DRB3 IKBKB MAP2K7 MAPK8IP1 PRDX3 STAT3
Entrez ID		9175
HPRD ID		05372
Ensembl ID		ENSG00000073803
Uniprot IDs		O43283
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Response To Cytokine Response To Stress Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Immune System Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Response To Organic Substance Immune Response-regulating Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of JUN Kinase Activity JNK Cascade Defense Response Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Peptidyl-cysteine Oxidation Response To Tumor Necrosis Factor Positive Regulation Of Immune Response Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Antigen Receptor-mediated Signaling Pathway Activation Of Innate Immune Response Regulation Of JNK Cascade Phosphorylation Intracellular Signal Transduction Cellular Response To Organic Substance Cellular Response To Sorbitol Regulation Of Kinase Activity Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Stress-activated MAPK Cascade Intracellular Receptor Signaling Pathway Regulation Of Immune Response
Tagcloud ?