SYT12

Description		synaptotagmin 12
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse Presynapse
	Molecular Function	SNARE Binding Calcium-dependent Phospholipid Binding Calcium Ion Sensor Activity
	Biological Process	Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Spontaneous Exocytosis Of Neurotransmitter Long-term Synaptic Potentiation Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways		Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		2 interacting genes: CFTR DNAJC5
Entrez ID		91683
HPRD ID		07337
Ensembl ID		ENSG00000173227
Uniprot IDs		B0AZL9 Q8IV01
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Lysosomal Membrane Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization ATP-dependent Protein Binding Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Chromaffin Granule Membrane Amelogenesis Regulation Of Vesicle-mediated Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Regulation Of Synaptic Vesicle Cycle Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Synaptic Vesicle Exocytosis Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Azurophil Granule Membrane Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport
Tagcloud ?