NEURL1

Gene Name		neuralized E3 ubiquitin protein ligase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Cell Junction Dendritic Spine Perikaryon Postsynaptic Membrane Perinuclear Region Of Cytoplasm Apical Dendrite
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Translation Factor Activity, Non-nucleic Acid Binding
	Biological Process	Regulation Of Translation Protein Monoubiquitination Notch Signaling Pathway Sperm Axoneme Assembly Nervous System Development Lactation Negative Regulation Of Cell Proliferation Sperm Motility Positive Regulation Of Apoptotic Process Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Cellular Response To Amino Acid Stimulus Positive Regulation Of Synapse Maturation
Pathways		Signaling by NOTCH1 HD Domain Mutants in Cancer Constitutive Signaling by NOTCH1 HD Domain Mutants Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH NOTCH2 Activation and Transmission of Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Signaling by NOTCH2 Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: UBE2D1 UBE2H UBE2N
Entrez ID		9148
HPRD ID		04815
Ensembl ID		ENSG00000107954
Uniprot IDs		B4DS86 O76050
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of Ubiquitin-protein Transferase Activity Cellular Macromolecule Catabolic Process Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Proteolysis Regulation Of Innate Immune Response Catabolic Process Regulation Of Histone Ubiquitination DNA Double-strand Break Processing Immune Response-regulating Signaling Pathway Positive Regulation Of Transferase Activity Positive Regulation Of Immune Response Cellular Protein Modification Process Postreplication Repair Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Innate Immune Response Regulation Of Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Mitotic Spindle Assembly Checkpoint DNA Catabolic Process, Exonucleolytic Regulation Of Organelle Organization Histone Ubiquitination Positive Regulation Of DNA Repair Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Chromosome Segregation Spindle Checkpoint
Tagcloud ?