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CERS5

Description ceramide synthase 5
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
Molecular Function
  • DNA Binding
  • Transferase Activity
  • Sphingosine N-acyltransferase Activity
Biological Process
  • Lipid Metabolic Process
  • Sphingolipid Metabolic Process
  • Oligodendrocyte Development
  • Sphingolipid Biosynthetic Process
  • Ceramide Biosynthetic Process
Pathways
  • Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 27618447 27618448)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hypertension ( 27618447 27618448)
  • Lymphocyte count ( 32888494)
  • Mean arterial pressure ( 27618448)
  • Schizophrenia ( 33169155)
  • Systolic blood pressure ( 27618447 27618448 28739976)
Novel Interacting Genes 1 novel interacting genes: CHPF
Interacting Genes
Entrez ID 91012
HPRD ID 13963
Ensembl ID ENSG00000139624
Uniprot IDs Q8N5B7
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Acetylgalactosaminyltransferase Activity
  • Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
  • N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity
  • Chondroitin Sulfate Proteoglycan Biosynthetic Process
  • Chondroitin Sulfate Proteoglycan Metabolic Process
  • Golgi Cisterna Membrane
  • Proteoglycan Biosynthetic Process
  • Proteoglycan Metabolic Process
  • Protein O-linked Glycosylation
  • Glycosyltransferase Activity
  • Glycoprotein Biosynthetic Process
  • Glycoprotein Metabolic Process
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