UCN2

Description		urocortin 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Hormone Binding Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels
Pathways		Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 25082827 28067908)
Interacting Genes		2 interacting genes: CRHR2 IL10RB
Entrez ID		90226
HPRD ID		16171
Ensembl ID		ENSG00000145040
Uniprot IDs		Q96RP3
PDB IDs		2RMG 3N95
Enriched GO Terms of Interacting Partners?		Corticotropin-releasing Hormone Receptor Activity Corticotrophin-releasing Factor Receptor Activity Interleukin-10 Receptor Activity Interleukin-28 Receptor Complex Cellular Response To Corticotropin-releasing Hormone Stimulus Type III Interferon-mediated Signaling Pathway Interleukin-10-mediated Signaling Pathway Positive Regulation Of Cellular Respiration G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Cellular Respiration Positive Regulation Of Receptor Signaling Pathway Via STAT Long-term Synaptic Potentiation Axon Terminus Coreceptor Activity Cellular Response To Virus Interferon-mediated Signaling Pathway Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cell Surface Receptor Signaling Pathway
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