PHLDB2

Name	pleckstrin homology like domain family B member 2
Structure
Interactors	5 interactors: CLK1 FLNC USP7 YWHAG YWHAQ
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Cell Projection Intermediate Filament Cytoskeleton Basal Cortex Anchoring Junction
	Molecular Function	Protein Binding Cadherin Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Migration Establishment Of Cell Polarity Establishment Of Protein Localization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Basement Membrane Organization Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells
GWAS	Atrial fibrillation ( 29892015 30061737 ) Cognitive performance ( 20125193 ) Crohn's disease-related phenotypes ( 25557950 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) PR interval ( 30046033 32439900 )
Entrez ID	90102
HPRD ID	06611
Ensembl ID	ENSG00000144824
Uniprot IDs	Q86SQ0
PDB IDs	8WHJ 8WHK 8WHM
GO Terms Enriched among Interactors ?	Focal Adhesion Negative Regulation Of TORC1 Signaling TORC1 Signaling Regulation Of TORC1 Signaling Negative Regulation Of TOR Signaling TOR Signaling Regulation Of TOR Signaling Protein Kinase C Inhibitor Activity Symbiont-mediated Disruption Of Host Cell PML Body Protein Targeting Protein Domain Specific Binding Protein Stabilization Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Cellular Response To Nutrient Levels Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Monoubiquitinated Protein Deubiquitination