UBE3B

Description		ubiquitin protein ligase E3B
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Postsynaptic Density Synapse Postsynapse Glutamatergic Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Transferase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Postsynapse Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 20864672) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Mean corpuscular hemoglobin ( 32888494) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Polymyositis ( 26362759) Pork consumption ( 32066663) PR interval ( 32439900) Total cholesterol levels ( 30275531 33339817)
Interacting Genes		8 interacting genes: CDC34 EPAS1 HIF1A HRAS MYC UBE2N UBE2V1 UBE2V2
Entrez ID		89910
HPRD ID		06993
Ensembl ID		ENSG00000151148
Uniprot IDs		Q7Z3V4
PDB IDs
Enriched GO Terms of Interacting Partners?		UBC13-MMS2 Complex Ubiquitin Conjugating Enzyme Complex Positive Regulation Of Protein K63-linked Ubiquitination Regulation Of Post-translational Protein Modification Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Error-free Postreplication DNA Repair Regulation Of Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Postreplication Repair Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of MiRNA Metabolic Process Regulation Of Protein Modification Process Protein K63-linked Ubiquitination Protein Polyubiquitination Cis-regulatory Region Sequence-specific DNA Binding Nucleoplasm Regulation Of MiRNA Metabolic Process Intracellular Oxygen Homeostasis Positive Regulation Of Protein Ubiquitination Cellular Response To Stress Positive Regulation Of Post-translational Protein Modification Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Protein Neddylation Positive Regulation Of Macromolecule Metabolic Process Cellular Response To Oxygen Levels Response To Stress Regulation Of DNA Metabolic Process Epithelial Cell Maturation DNA Double-strand Break Processing Nucleic Acid Metabolic Process Embryonic Placenta Development Regulation Of Cellular Response To Stress Protein Dimerization Activity Regulation Of Protein Ubiquitination Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Metabolic Process Protein Ubiquitination Regulation Of DNA Repair Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription Coactivator Binding Regulation Of Protein Metabolic Process Protein-containing Complex Positive Regulation Of DNA Metabolic Process DNA Damage Response Response To Hypoxia
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