P4HA2

Name	prolyl 4-hydroxylase subunit alpha 2
Structure
Novel Interactors	2 novel interactors: CD86 PRKAR2A
Interactors	7 interactors: CLNK CREB3 FHL3 OGT P4HB PRRC2A TNS4
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity
Pathways	Collagen biosynthesis and modifying enzymes
Drugs	Proline
GWAS	Asthma ( 31619474 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Crohn's disease ( 22412388 28067908 ) Giant cell arteritis ( 28041642 ) Height ( 28552196 ) Inflammatory bowel disease ( 28067908 ) Intracranial aneurysm ( 33199917 ) Intraocular pressure ( 29617998 ) Subcortical volume (MOSTest) ( 32665545 ) Sum eosinophil basophil counts ( 27863252 ) Ulcerative colitis ( 28067908 ) Youthful appearance (self-reported) ( 32339537 )
Entrez ID	8974
HPRD ID	11862
Ensembl ID	ENSG00000072682
Uniprot IDs	O15460 Q05DA4
PDB IDs	6EVL 6EVM 6EVN 6EVO 6EVP 7ZSC
GO Terms Enriched among Interactors ?	Focal Adhesion