EIF2B4

Description		eukaryotic translation initiation factor 2B subunit delta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Initiation Factor Binding
	Biological Process	Ovarian Follicle Development Cytoplasmic Translational Initiation Translation Translational Initiation Regulation Of Translation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Animal Organ Development T Cell Receptor Signaling Pathway
Pathways		Recycling of eIF2:GDP
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Non-oily fish consumption ( 32066663)
Interacting Genes		3 interacting genes: EIF2B2 EIF2S1 EIF2S2
Entrez ID		8890
HPRD ID		09459
Ensembl ID		ENSG00000115211
Uniprot IDs		B4DUP5 E7ERK9 F8W8L6 Q71US4 Q9HBP7 Q9UI10
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z 7D43 7D44 7D45 7D46 7F64 7F66 7F67 7KMF 7L70 7L7G 7RLO 7TRJ 7VLK 8TQO 8TQZ
Enriched GO Terms of Interacting Partners?		Translation Initiation Factor Activity Translational Initiation Eukaryotic Translation Initiation Factor 2 Complex Translation Cytoplasmic Translational Initiation Response To Heat Regulation Of Translational Initiation Translation Initiation Ternary Complex Response To Temperature Stimulus Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot Male Germ Cell Proliferation Macromolecule Biosynthetic Process Response To Kainic Acid Negative Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Type B Pancreatic Cell Apoptotic Process Eukaryotic Translation Initiation Factor 2B Complex HRI-mediated Signaling Regulation Of Translation In Response To Endoplasmic Reticulum Stress Mitochondrial Respirasome Assembly Regulation Of Translational Initiation In Response To Stress Regulation Of Translation Cellular Response To Manganese Ion Formation Of Translation Preinitiation Complex PERK-mediated Unfolded Protein Response Response To Manganese Ion Eukaryotic 48S Preinitiation Complex Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Apoptotic Process Regulation Of Translation In Response To Stress Translation Factor Activity, RNA Binding Translation Initiation Factor Binding Oligodendrocyte Development Protein Metabolic Process Stress Granule Assembly ER-nucleus Signaling Pathway Integrated Stress Response Signaling Negative Regulation Of Translational Initiation Ovarian Follicle Development Synapse Cellular Response To Heat Regulation Of Epithelial Cell Apoptotic Process Mitophagy Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Endoplasmic Reticulum Unfolded Protein Response Glial Cell Development Autophagy Of Mitochondrion Ribosome Binding
Tagcloud ?