TNFSF9

Description		TNF superfamily member 9
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Tumor Necrosis Factor Receptor Superfamily Binding
	Biological Process	Immune Response Cell Communication Signal Transduction Cell-cell Signaling Signaling Positive Regulation Of Activated T Cell Proliferation Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Cytotoxic T Cell Differentiation
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Novel Interacting Genes		2 novel interacting genes: CLPP KHSRP
Interacting Genes		3 interacting genes: TNFRSF9 TRAF1 TRAF2
Entrez ID		8744
HPRD ID		05861
Ensembl ID		ENSG00000125657
Uniprot IDs		A0A0U5J8I0 P41273
PDB IDs		2X29 6A3V 6BWV 6CPR 6CU0 6D3N 6FIB 6MGE 6MGP
Enriched GO Terms of Interacting Partners?		Thioesterase Binding Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor-mediated Signaling Pathway Signaling Adaptor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity TORC2 Complex Disassembly Positive Regulation Of DNA-binding Transcription Factor Activity TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Endopeptidase Clp Complex Cell Death Programmed Cell Death Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Sphingolipid Binding Regulation Of MRNA Stability Regulation Of RNA Stability IRE1-TRAF2-ASK1 Complex CD27 Signaling Pathway Tumor Necrosis Factor Receptor Superfamily Complex Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding ATP-dependent Peptidase Activity Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin Protein Ligase Binding CD40 Receptor Complex Regulation Of MRNA Metabolic Process CD40 Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of JUN Kinase Activity Interleukin-17-mediated Signaling Pathway Mitochondrial Protein Catabolic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of Apoptotic Signaling Pathway TORC2 Signaling Cellular Response To Nitric Oxide Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding Cellular Response To Reactive Nitrogen Species Negative Regulation Of Nitric Oxide Biosynthetic Process Exosome (RNase Complex) Negative Regulation Of Lipoprotein Particle Clearance 3'-UTR-mediated MRNA Destabilization Cytokine-mediated Signaling Pathway Regulation Of Low-density Lipoprotein Particle Clearance Response To Nitric Oxide Programmed Necrotic Cell Death
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