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CTSF
Gene Name
cathepsin F
Image
Gene Ontology Annotations
Cellular Component
Lysosome
Vesicle
Lysosomal Lumen
Extracellular Vesicular Exosome
Molecular Function
Cysteine-type Endopeptidase Activity
Biological Process
Proteolysis
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways
MHC class II antigen presentation
Adaptive Immune System
Drugs
[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester
[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester
4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide
Benzoyl-Arginine-Alanine-Methyl Ketone
WRR-99
WRR-112
HOMOPHENYLALANINYLMETHANE
BENZOYL-TYROSINE-ALANINE-METHYL KETONE
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-protein Interactions
1 interactors:
CD74
Entrez ID
8722
HPRD ID
04643
Ensembl ID
ENSG00000174080
Uniprot IDs
Q9UBX1
PDB IDs
1D5U
1M6D
Enriched GO Terms of Interacting Partners
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Macrophage Migration Inhibitory Factor Signaling Pathway
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Negative Regulation Of Mature B Cell Apoptotic Process
Positive Thymic T Cell Selection
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Negative Regulation Of B Cell Apoptotic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Thymic T Cell Selection
Negative T Cell Selection
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Antigen Processing And Presentation Of Endogenous Antigen
Regulation Of B Cell Apoptotic Process
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Thymic T Cell Selection
Positive Regulation Of Macrophage Cytokine Production
Prostaglandin Biosynthetic Process
Positive Regulation Of Neutrophil Chemotaxis
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response
Regulation Of Macrophage Activation
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Granulocyte Chemotaxis
Positive Regulation Of Type 2 Immune Response
Chaperone Mediated Protein Folding Requiring Cofactor
Positive T Cell Selection
Positive Regulation Of Cytokine-mediated Signaling Pathway
Positive Regulation Of Response To Cytokine Stimulus
Regulation Of Neutrophil Chemotaxis
Prostaglandin Metabolic Process
Regulation Of Neutrophil Migration
Negative Regulation Of T Cell Differentiation
Regulation Of Granulocyte Chemotaxis
Positive Regulation Of B Cell Proliferation
T Cell Selection
Positive Regulation Of Chemokine Production
Negative Regulation Of Peptide Secretion
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Type 2 Immune Response
Icosanoid Biosynthetic Process
Negative Regulation Of Lymphocyte Differentiation
Positive Regulation Of Cytokine Production Involved In Immune Response
Unsaturated Fatty Acid Biosynthetic Process
Negative Regulation Of Leukocyte Apoptotic Process
Regulation Of Chemokine Production
'de Novo' Posttranslational Protein Folding
Regulation Of B Cell Proliferation
'de Novo' Protein Folding
Regulation Of Lymphocyte Apoptotic Process
Tagcloud
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0e
1426a
219g
3072g
abhd16a
abhd5
acp2
alms1
apoa2
atp1a2
bft
col14a1
dars
decr1
ghrl
intron3
mc4r
mttp
nfkbia
nt5e
pfp
plat
ppp2r5d
rfc2
rragd
sdhd
serpinf1
tbc1d1
ube2h