CTSF

Gene Name		cathepsin F
Image
Gene Ontology Annotations	Cellular Component	Lysosome Vesicle Lysosomal Lumen Extracellular Vesicular Exosome
	Molecular Function	Cysteine-type Endopeptidase Activity
	Biological Process	Proteolysis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs		[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester [1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester 4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide Benzoyl-Arginine-Alanine-Methyl Ketone WRR-99 WRR-112 HOMOPHENYLALANINYLMETHANE BENZOYL-TYROSINE-ALANINE-METHYL KETONE
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		1 interactors: CD74
Entrez ID		8722
HPRD ID		04643
Ensembl ID		ENSG00000174080
Uniprot IDs		Q9UBX1
PDB IDs		1D5U 1M6D
Enriched GO Terms of Interacting Partners?		Macrophage Migration Inhibitory Factor Signaling Pathway Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Negative Regulation Of Mature B Cell Apoptotic Process Positive Thymic T Cell Selection Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of B Cell Apoptotic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Thymic T Cell Selection Negative T Cell Selection Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Antigen Processing And Presentation Of Endogenous Antigen Regulation Of B Cell Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Thymic T Cell Selection Positive Regulation Of Macrophage Cytokine Production Prostaglandin Biosynthetic Process Positive Regulation Of Neutrophil Chemotaxis Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Macrophage Activation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Type 2 Immune Response Chaperone Mediated Protein Folding Requiring Cofactor Positive T Cell Selection Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Neutrophil Chemotaxis Prostaglandin Metabolic Process Regulation Of Neutrophil Migration Negative Regulation Of T Cell Differentiation Regulation Of Granulocyte Chemotaxis Positive Regulation Of B Cell Proliferation T Cell Selection Positive Regulation Of Chemokine Production Negative Regulation Of Peptide Secretion Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Type 2 Immune Response Icosanoid Biosynthetic Process Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Cytokine Production Involved In Immune Response Unsaturated Fatty Acid Biosynthetic Process Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Chemokine Production 'de Novo' Posttranslational Protein Folding Regulation Of B Cell Proliferation 'de Novo' Protein Folding Regulation Of Lymphocyte Apoptotic Process
Tagcloud ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 rragd sdhd serpinf1 tbc1d1 ube2h