ALDH4A1

Gene Name		aldehyde dehydrogenase 4 family, member A1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	1-pyrroline-5-carboxylate Dehydrogenase Activity Aldehyde Dehydrogenase (NAD) Activity Electron Carrier Activity Identical Protein Binding
	Biological Process	Glutamate Biosynthetic Process Proline Metabolic Process Proline Biosynthetic Process Proline Catabolic Process Proline Catabolic Process To Glutamate 4-hydroxyproline Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Proline catabolism Metabolism of amino acids and derivatives
Drugs		NADH
Diseases
GWAS		Anorexia nervosa ( 23568457)
Protein-protein Interactions		2 interactors: APP ARG1
Entrez ID		8659
HPRD ID		06009
Ensembl ID		ENSG00000159423
Uniprot IDs		P30038
PDB IDs		3V9G 3V9H 3V9I
Enriched GO Terms of Interacting Partners?		Regulation Of L-arginine Import Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Response To Oxidative Stress Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Mammary Gland Involution Axon Choice Point Recognition Response To Selenium Ion Arginine Catabolic Process Neuron Remodeling Response To Herbicide Response To Methylmercury Response To Wounding Urea Cycle Collagen Biosynthetic Process Urea Metabolic Process Response To Manganese Ion Protein Homotrimerization Cellular Copper Ion Homeostasis Response To Vitamin E Arginine Metabolic Process Copper Ion Homeostasis Suckling Behavior Reproduction Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Response To Vitamin A Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cellular Response To Dexamethasone Stimulus Mating Behavior Protein Trimerization Response To Dexamethasone Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Reproductive Process Cellular Response To Glucagon Stimulus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Interleukin-4 Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Response To Zinc Ion Response To Amine Response To Interleukin-4 Axon Cargo Transport Mating
Tagcloud ?		abpp accordance acivicin ago aldehyde behind catalytic cytotoxic decades deconvolution dehydrogenases depth derivatives desired detail downregulation elucidate elucidated explanation explored functionalized intact never preference profiling proteomic unacceptable undesired validation