RNASET2

Name	ribonuclease T2
Structure
Novel Interactors	1 novel interactors: CEP43
Interactors	1 interactors: UBC
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Mitochondrion Mitochondrial Intermembrane Space Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity RNA Nuclease Activity Hydrolase Activity Lyase Activity Ribonuclease T2 Activity
	Biological Process	Immune System Process RNA Catabolic Process Innate Immune Response
Pathways	Neutrophil degranulation
Diseases	Cystic leukoencephalopathy without megalencephaly
GWAS	Allergic disease (asthma, hay fever or eczema) ( 29083406 ) Autoimmune thyroid disease ( 32581359 ) Crohn's disease ( 23850713 28067908 ) Endometrial cancer ( 24096698 ) Graves' disease ( 21841780 ) Huntington's disease progression ( 28642124 ) Inflammatory bowel disease ( 23128233 28067908 ) Lung adenocarcinoma ( 28604730 ) Lung cancer ( 28604730 ) Smooth-surface caries ( 24556642 ) Spontaneous preterm birth (preterm birth) ( 25599974 ) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926 ) Vitiligo ( 20526339 27723757 )
Entrez ID	8635
HPRD ID	10197
Ensembl ID	ENSG00000026297
Uniprot IDs	O00584
PDB IDs	3T0O