ITGA8

Gene Name		integrin, alpha 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Postsynaptic Density Dendritic Spine Membrane Integrin Alpha8-beta1 Complex Perikaryon Apical Part Of Cell
	Molecular Function	Metal Ion Binding
	Biological Process	Metanephros Development Kidney Development Cell-matrix Adhesion Integrin-mediated Signaling Pathway Brain Development Memory Single Organismal Cell-cell Adhesion Cell Projection Organization Extracellular Matrix Organization Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Substrate Adhesion-dependent Cell Spreading Inner Ear Morphogenesis Establishment Of Protein Localization Mesodermal Cell Differentiation Smooth Muscle Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation
Pathways		Molecules associated with elastic fibres Elastic fibre formation ECM proteoglycans Integrin cell surface interactions
Drugs
Diseases
GWAS		Parkinson's disease ( 19915575) Quantitative traits ( 19197348)
Protein-protein Interactions		4 interactors: FN1 ITGB1 NPNT VTN
Entrez ID		8516
HPRD ID		10361
Ensembl ID
Uniprot IDs		P53708
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Adhesion Mediated By Integrin Cell-matrix Adhesion Cell-substrate Adhesion Extracellular Matrix Organization Extracellular Structure Organization Calcium-independent Cell-matrix Adhesion Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Cell-substrate Adhesion Formation Of Primary Germ Layer Regulation Of Cell-substrate Adhesion Gastrulation Cell Adhesion Positive Regulation Of Cell Adhesion Endodermal Cell Differentiation Tissue Development Endoderm Formation Regulation Of Cell Adhesion Endoderm Development Embryonic Morphogenesis Positive Regulation Of Endocytosis Anatomical Structure Morphogenesis Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Anatomical Structure Formation Involved In Morphogenesis Regulation Of Endocytosis Regulation Of Cellular Response To Growth Factor Stimulus Cell Junction Assembly Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Embryo Development Cell Differentiation Positive Regulation Of Metabolic Process Pilomotor Reflex Regulation Of Collagen Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Smooth Muscle Cell Differentiation Positive Regulation Of Neuron Projection Development Leukocyte Migration Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Defense Response Formation Of Radial Glial Scaffolds Positive Regulation Of Cell Projection Organization Regulation Of Phosphorus Metabolic Process Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Cell Migration Angiogenesis
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