USP45

Gene Name		ubiquitin specific peptidase 45
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Zinc Ion Binding
	Biological Process	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: BMPR1B SMAD1 SMURF1 TGFBR1
Entrez ID		85015
HPRD ID		11667
Ensembl ID		ENSG00000123552
Uniprot IDs		Q70EL2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway BMP Signaling Pathway Regulation Of Cartilage Development Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ossification Signal Transduction By Phosphorylation Positive Regulation Of Cartilage Development Tissue Development Pattern Specification Process Positive Regulation Of Osteoblast Differentiation Skeletal System Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Gamete Generation Negative Regulation Of Cell Proliferation Positive Regulation Of Ossification Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Sexual Reproduction Multicellular Organismal Reproductive Process Regulation Of Osteoblast Differentiation Multicellular Organism Reproduction Cell Surface Receptor Signaling Pathway Ovarian Cumulus Expansion Negative Regulation Of Chondrocyte Proliferation Reproduction Cellular Protein Modification Process Regulation Of Cellular Response To Growth Factor Stimulus Cartilage Development Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Differentiation Single Organism Reproductive Process Bone Development Gonad Development Development Of Primary Sexual Characteristics Connective Tissue Development Reproductive Process Protein Phosphorylation Skeletal System Morphogenesis Positive Regulation Of Cell Projection Organization Cell Fate Commitment Sex Differentiation Regulation Of Apoptotic Process Oogenesis Stage
Tagcloud ?		acetobutylicum amylase amys bacillus cassette clostridium conservation deduced dnaj frame gram heat inverted lactis lactococcus monocistronic mutagenesis nizo palindromic preceded puc19 r5 reading shock subtilis taaaat threefold ttgcca vegetative