DOC2B

Description		double C2 domain beta
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane SNARE Complex Synapse Presynapse
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Metal Ion Binding
	Biological Process	Chemical Synaptic Transmission Intracellular Protein Localization Positive Regulation Of Vesicle Fusion Positive Regulation Of Insulin Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Spontaneous Neurotransmitter Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion
Pathways
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: DYNLT1 STXBP1 UNC13B
Entrez ID		8447
HPRD ID		05196
Ensembl ID		ENSG00000272636
Uniprot IDs		Q14184
PDB IDs
Enriched GO Terms of Interacting Partners?		Dense Core Granule Exocytosis Neuronal Dense Core Vesicle Exocytosis Regulation Of Synaptic Vesicle Priming Secretory Granule Localization Establishment Of Organelle Localization Syntaxin-1 Binding Synaptic Vesicle Priming Calcium-ion Regulated Exocytosis Vesicle Docking Involved In Exocytosis Organelle Localization Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Positive Regulation Of Transport Regulated Exocytosis Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Vesicle Docking Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Positive Regulation Of Synaptic Vesicle Priming Intracellular Transport Of Viral Protein In Host Cell Dense Core Granule Priming Exocytosis Axon Target Recognition Regulation Of Acrosomal Vesicle Exocytosis Extrinsic Component Of Presynaptic Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Glutamate Secretion, Neurotransmission Negative Regulation Of Synaptic Transmission, GABAergic Establishment Of Localization In Cell Regulation Of Transport Platelet Degranulation Regulation Of Glutamate Secretion, Neurotransmission Positive Regulation Of Secretion By Cell Acrosomal Vesicle Exocytosis Chemical Synaptic Transmission Positive Regulation Of Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Trans-synaptic Signaling Synaptic Signaling Modulation Of Inhibitory Postsynaptic Potential Synaptic Vesicle Maturation Intracellular Transport Of Virus Secretion By Cell Calcium Ion-regulated Exocytosis Of Neurotransmitter Host Cell Secretory Vesicle Regulation Of Protein-containing Complex Assembly Positive Regulation Of Glutamate Secretion
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