MON1A

Description		MON1 vesicular trafficking associated A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Mon1-Ccz1 Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Protein Targeting To Vacuole Protein Secretion Vesicle-mediated Transport
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062 29273807 25673413) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		1 novel interacting genes: FYCO1
Interacting Genes		6 interacting genes: GFI1B MAPK6 RABGEF1 RGS2 TAB1 VPS33A
Entrez ID		84315
HPRD ID		17586
Ensembl ID		ENSG00000164077
Uniprot IDs		Q86VX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Septin Cytoskeleton Negative Regulation Of Glycine Import Across Plasma Membrane Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Intracellular Transport Organelle Localization Lysosome Localization Negative Regulation Of Kit Signaling Pathway Negative Regulation Of Mast Cell Cytokine Production Autophagosome Vesicle Localization Kit Signaling Pathway Adenylate Cyclase Inhibitor Activity Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Relaxation Of Smooth Muscle Relaxation Of Vascular Associated Smooth Muscle Mitogen-activated Protein Kinase P38 Binding Cellular Localization Establishment Of Localization In Cell Endosome Transport Along Microtubule Mast Cell Migration Negative Regulation Of Mast Cell Degranulation Cytoskeleton-dependent Intracellular Transport CORVET Complex Late Endosome Plus-end-directed Vesicle Transport Along Microtubule Plus-end-directed Organelle Transport Along Microtubule Positive Regulation Of Autophagosome Maturation Positive Regulation Of CGAS/STING Signaling Pathway Microtubule-based Transport Presynaptic Endosome Clathrin Complex Intracellular Signaling Cassette Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Mast Cell Activation
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