KREMEN1

Gene Name		kringle containing transmembrane protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding
	Biological Process	Cell Communication Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation negative regulation of TCF-dependent signaling by WNT ligand antagonists XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS		Waist-hip ratio ( 20935629)
Protein-protein Interactions		1 interactors: DKK1
Entrez ID		83999
HPRD ID		11182
Ensembl ID		ENSG00000183762
Uniprot IDs		Q96MU8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Heart Induction By Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Heart Induction By Regulation Of Canonical Wnt Signaling Pathway Regulation Of Endodermal Cell Fate Specification Negative Regulation Of Mesodermal Cell Fate Specification Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Negative Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Cell Fate Specification Negative Regulation Of Mesoderm Development Wnt Signaling Pathway Involved In Somitogenesis Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Fate Commitment Positive Regulation Of Cell Fate Commitment Extracellular Negative Regulation Of Signal Transduction Regulation Of Cell Fate Specification Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Cardiac Muscle Tissue Development Negative Regulation Of Receptor Activity Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Embryonic Development Regulation Of Receptor Internalization Regulation Of Cell Fate Commitment Regulation Of Gastrulation Face Morphogenesis Head Morphogenesis Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Striated Muscle Tissue Development Negative Regulation Of Muscle Organ Development Face Development Regulation Of Pathway-restricted SMAD Protein Phosphorylation Endoderm Formation Body Morphogenesis Regulation Of Cardiac Muscle Tissue Development Regulation Of Skeletal Muscle Tissue Development Regulation Of BMP Signaling Pathway Somitogenesis Endoderm Development Mesoderm Formation Mesoderm Morphogenesis Hair Follicle Development Hair Cycle Process Somite Development Regulation Of Striated Muscle Cell Differentiation Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Hair Cycle Regulation Of Embryonic Development Segmentation
Tagcloud ?		22q12 5p15 acc accs adrenocortical cdc27 cna cnas corroborate ctnnb1 denote exclusive exome gnas homozygous incompletely mutually nf2 ontology rb1 recurrently repressors scn7a sdk1 somatic synonymous tert utilize znrf3