SESN2

Gene Name		sestrin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Fatty Acid Beta-oxidation Autophagy Response To Glucose Mitochondrial DNA Metabolic Process Response To Insulin Protein Kinase B Signaling Glucose Import Triglyceride Homeostasis Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Regulation Of Response To Reactive Oxygen Species Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: MDM2 PRDX1 ULK1
Entrez ID		83667
HPRD ID		06378
Ensembl ID		ENSG00000130766
Uniprot IDs		P58004
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Reactive Oxygen Species Cellular Response To UV-C Cellular Response To Vitamin B1 Cellular Response To Nutrient Levels Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Regulation Of Nucleocytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Cellular Response To Extracellular Stimulus Cellular Response To Stress Regulation Of Intracellular Protein Transport Catabolic Process Traversing Start Control Point Of Mitotic Cell Cycle Response To Vitamin B1 Response To Ether Negative Regulation Of Collateral Sprouting Response To Oxidative Stress Response To Nutrient Levels Regulation Of Intracellular Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Response To Extracellular Stimulus Response To Inorganic Substance Response To UV-C Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Export From Nucleus Cerebellar Granule Cell Differentiation Regulation Of Signal Transduction Positive Regulation Of Macroautophagy Regulation Of Protein Transport Cerebellar Granular Layer Morphogenesis Hydrogen Peroxide Catabolic Process Response To Magnesium Ion Regulation Of Signaling Cellular Response To Antibiotic Negative Regulation Of Cell Cycle Arrest Regulation Of Establishment Of Protein Localization Removal Of Superoxide Radicals Cellular Response To Superoxide Cerebellar Granular Layer Development Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Migration In Hindbrain Cellular Response To Toxic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle G1/S Phase Transition Protein Destabilization Natural Killer Cell Mediated Cytotoxicity Response To Stress Regulation Of Protein Localization Natural Killer Cell Mediated Immunity Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Tagcloud ?		activates anticancer atf4 attenuated autophagy cebpb chip ddit4 depletion effectively elusive exo genomic greatly largely mitochondria mtorc1 nude pad pan perturbation potentials remain resolution responsive triple unveiled xenograft yw3