HIST1H3H

Gene Name		histone cluster 1, H3h
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nucleosome Extracellular Region Nucleus Nucleoplasm Membrane Protein Complex Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Silencing At RDNA Chromatin Organization DNA Replication-dependent Nucleosome Assembly Blood Coagulation Gene Expression DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Silencing
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase PKMTs methylate histone lysines Regulatory RNA pathways RNA Polymerase I Promoter Clearance HDMs demethylate histones Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression Factors involved in megakaryocyte development and platelet production PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: HTT NASP PHF1 TRIM24 ZDHHC17
Entrez ID		8357
HPRD ID		11912
Ensembl ID		ENSG00000203813
Uniprot IDs		P68431
PDB IDs		1CS9 1CT6 1Q3L 2B2T 2B2U 2B2V 2B2W 2C1J 2C1N 2CV5 2KWJ 2KWK 2L75 2LBM 2M0O 2RI7 2UXN 3A1B 3AFA 3AVR 3AYW 3AZE 3AZF 3AZG 3AZH 3AZI 3AZJ 3AZK 3AZL 3AZM 3AZN 3B95 3KMT 3KQI 3LQI 3LQJ 3O34 3O35 3O37 3RIG 3RIY 3U4S 3U5N 3U5O 3U5P 3UEE 3UEF 3UIG 3UII 3UIK 3V43 3W96 3W97 3W98 3W99 3ZG6 3ZVY 4A0J 4A0N 4A7J 4BD3 4F4U 4F56 4FWF 4HON 4I51
Enriched GO Terms of Interacting Partners?		Neural Plate Formation Biosynthetic Process Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Response To Estrogen Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Histone H3-K27 Methylation Lactate Biosynthetic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Vitamin D Receptor Signaling Pathway Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Response To CGMP Serotonin Transport Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import DNA Replication-dependent Nucleosome Assembly Protein Transport Establishment Of Protein Localization Citrulline Metabolic Process Lactate Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Histone H3-K27 Methylation Macromolecule Biosynthetic Process Urea Cycle Neurotransmitter Uptake Cellular Response To Organic Cyclic Compound Urea Metabolic Process Regulation Of Histone H3-K27 Methylation Cellular Response To Lipid Thalamus Development Striatum Development Paraxial Mesoderm Morphogenesis Neural Plate Development Amino Acid Import Regulation Of Intracellular Signal Transduction Insemination Metal Ion Homeostasis Regulation Of Synaptic Transmission, Dopaminergic Response To Steroid Hormone Negative Regulation Of Histone Methylation Determination Of Adult Lifespan Grooming Behavior Lipoprotein Transport
Tagcloud ?