KDM5D

Description		lysine demethylase 5D
Image
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity Histone Demethylase Activity Histone H3K4 Demethylase Activity Histone H3K4me/H3K4me2/H3K4me3 Demethylase Activity Metal Ion Binding Nuclear Androgen Receptor Binding Dioxygenase Activity
	Biological Process	T Cell Antigen Processing And Presentation Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Androgen Receptor Signaling Pathway
Pathways		HDMs demethylate histones
Drugs		Ascorbic acid
Diseases
GWAS		Autism ( 32996047)
Interacting Genes		3 interacting genes: H3-4 PCGF6 PEX14
Entrez ID		8284
HPRD ID		02464
Ensembl ID		ENSG00000012817
Uniprot IDs		A0A384MR42 B4E1Y0 Q9BY66
PDB IDs		2E6R 2YQE
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Translocation Peroxisome Transport Along Microtubule Protein Import Into Peroxisome Matrix, Docking Peroxisomal Importomer Complex Spermatogonial Cell Division Protein Import Into Peroxisome Matrix, Substrate Release DNA Replication-dependent Chromatin Assembly Protein Transmembrane Transporter Activity Protein Unfolding Protein Import Into Peroxisome Matrix, Receptor Recycling Receptor Recycling Peroxisomal Membrane Transport Microtubule Anchoring Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Peroxisome Organization Chromatin Remodeling PcG Protein Complex PRC1 Complex Negative Regulation Of Protein Binding Intracellular Protein Transmembrane Transport Chromatin Organization Beta-tubulin Binding Regulation Of Protein Binding Receptor Metabolic Process Condensed Nuclear Chromosome Heterochromatin Protein Monoubiquitination
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