TXNDC5

Description		thioredoxin domain containing 5
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endomembrane System Azurophil Granule Lumen Lysosomal Lumen Intracellular Organelle Lumen Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Isomerase Activity
	Biological Process	Protein Folding Negative Regulation Of Apoptotic Process
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) High chromosomal aberration frequency (chromatid type) ( 31586183) Mean corpuscular hemoglobin ( 32888494) Pelvic organ prolapse ( 32184442)
Interacting Genes		29 interacting genes: APP AR BLZF1 CEBPA EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA OGT PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6 UBQLN2
Entrez ID		81567
HPRD ID		18249
Ensembl ID		ENSG00000239264
Uniprot IDs		A0A024QZV0 Q8NBS9
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX 8EKY
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Protein Glycosylation Macromolecule Glycosylation Glycosylation Hair Cycle
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